IB+ND+EDS INDICATIONS
Nobilis® IB+ND+EDS is a combined inactivated vaccine for the protection of layers and breeders against Egg Drop Syndrome ’76 and for the booster vaccination of breeding chickens against Newcastle Disease and Massachusetts type of Infectious Bronchitis.
COMPOSITION
Nobilis® IB+ND+EDS contains immunogenic strains of Infectious Bronchitis virus (Massachusetts), and Newcastle Disease virus and the BC strain 14 Egg Drop Syndrome ’76 virus.
Each 0,5 ml dose of Nobilis® IB+ND+EDS contains immunogenic strains of Infectious Bronchitis virus (Massachusetts) (inducing ≥ 6,0 log2 HI units), Newcastle Disease virus, (containing ≥ to 50 PD50 units), and BC strain 14 of Egg Drop Syndrome ’76 virus (inducing ≥ 6,5 log2 HI units). The viruses have
been inactivated with formalin and subsequently suspended in the water phase of a water-in-oil emulsion.
DIRECTIONS FOR USE – USE ONLY AS DIRECTED
Shake well before use and at regular intervals during the vaccination process.

ADMINISTRATION
- Each chicken should be given 0,5 ml of the vaccine intramuscularly into the breast muscle or subcutaneously into the back of the neck. (Intramuscular into the breast muscle, the needle should be pointed in the direction of the chicken’s head to prevent the needle from entering the body cavity).
- Allow the vaccine to gradually reach room temperature (20 °C to 25 °C) prior to use.
- Shake well before use and at regular intervals during the vaccination process.
- Remove the aluminum over seal and the vaccine is ready for use.
- Inject all the chickens in the flock.
RECOMMENDED VACCINATION PROGRAMME
Nobilis® IB+ND+EDS should be given to chickens around 16 to 20 weeks of age, but not less than 4 weeks before the expected onset of lay.
For an optimal booster effect, the chickens must be primed with live vaccines of the separate component strains.
The best results will be obtained if vaccination with inactivated IB vaccine takes place 6 weeks or more after administering the live vaccine but under no
circumstances should it be done earlier than 4 weeks after priming.
IMMUNITY
If priming and subsequent vaccination have been carried out correctly the chickens will develop antibodies at a level which provides protection against Egg Drop Syndrome ’76, Newcastle Disease and production losses caused by the Massachusetts serotype of Infectious Bronchitis.
STORAGE
- Store in the dark between 2 °C and 8 °C.
- Do not freeze.
- Avoid prolonged or repetitive exposure to high ambient temperatures following withdrawal from the refrigerator prior to use.
- Protect from direct sunlight.
WITHDRAWAL PERIOD
Do not market chickens for slaughter for at least 6 weeks after vaccination.
PRESENTATION
Bottles containing 500 ml sufficient for 1 000.